Obstetric complications in schizophrenia

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Obstetric complications in schizophrenia

(BDQ). They were also interviewed using a semi-structured schedule focussed on the phenomenon of bodily change. Each subject was also asked to attempt an estimation of the size of body parts on a linear presentation. All groups over-estimated their body size, with females significantly more so than males. Apart from a non-significant trend for female schizophrenics to over-estimate to a greater...

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Familial liability, obstetric complications and childhood development abnormalities in early onset schizophrenia: a case control study

BACKGROUND Genetic and environmental risk factors and gene-environment interactions are linked to higher likelihood of developing schizophrenia in accordance with the neurodevelopmental model of disease; little is known about risk factors and early development in early-onset schizophrenia (EOS) and very early-onset schizophrenia (VEOS). METHODS We present a case-control study of a sample of 2...

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Schizophrenia, Cancer and Obstetric Complications in an Evolutionary Perspective-An Empirically Based Hypothesis

OBJECTIVE Patients diagnosed with schizophrenia have reduced fecundity and premature mortality (both accidental and violent) with no obvious compensatory advantages among kin. The prevalence of the disorder is around 0.7/1%, higher than the expected prevalence of spontaneous mutations. Genes favoring schizophrenia may have been positively selected in the environment of evolutionary adaptation. ...

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Gene-environment interaction and covariation in schizophrenia: the role of obstetric complications.

While genetic factors account for a significant proportion of liability to schizophrenia, a body of evidence attests to a significant environmental contribution. Understanding the mechanisms through which genetic and environmental factors coalesce in influencing schizophrenia is critical for elucidating the pathways underlying psychotic illness and for developing primary prevention strategies. ...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 1995

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.167.5.694b